Premier League: Manchester United vs Tottenham Odds, Analysis, & Picks

Quinn Allen
By: Quinn Allen
Soccer Picks
Manchester United vs Tottenham Odds, Analysis, & Picks

Photo courtesy of Shutter Fotos (Flickr), CC by 2.0

Manchester United welcome Tottenham to Old Trafford on Saturday, with kickoff scheduled for 12:30 p.m. ET in this Matchweek 6 encounter. The Red Devils have endured a disappointing start to the campaign, collecting just five points from their opening five league matches. United drew 1-1 with Fulham in their last outing, while Tottenham remain winless in the Premier League after a 3-2 defeat to Aston Villa. Read below for our Manchester United vs Tottenham picks.

Highlights

  • Manchester United and Tottenham clash on Saturday at Old Trafford
  • Both clubs have struggled for consistency through their opening five league matches
  • Keep reading for the odds, preview, and picks

Odds courtesy of TonyBet.

Manchester United vs Tottenham Odds

Soccer betting sites have Man United as a sizable -139 favorite to win Saturday’s clash. Spurs, meanwhile, sit at +350 odds. A draw is priced at +320, and the O/U is set at three goals.

The Red Devils are unbeaten in their last two games against Tottenham, but the North Londoners won the previous four meetings across all competitions.

Manchester United vs Tottenham Analysis

After a brilliant 2025-26 campaign, United have not looked like the same side so far. Michael Carrick’s men sit in 12th place, with a poor 1-2-2 record. The Red Devils’ only league win came over newly promoted Ipswich Town, and that was on August 30. Since then, they've won just once across all competitions, suffering a League Cup exit to Brighton and a defeat in the Manchester derby in mid-September.

Outside that five-goal performance against Ipswich, Man United have scored just three times in their other four matches, and have conceded eight goals overall. Carrick’s attack has been toothless, but this fixture offers a chance to change the narrative. Spurs have conceded six in their last two games.

The start of the 2026-27 campaign has been a complete disaster for Tottenham. After barely steering clear of relegation last season, Spurs sit dead last with a measly two points, and if they don't find their form soon, this could be another relegation battle. Roberto De Zerbi has already publicly criticized his players for a lack of effort, but they did play better on September 19 against Villa before the international break.

While Tottenham still suffered defeat, they finally showed signs of life in the final third, scoring their first two Premier League goals of the season. The result was disappointing, but the improved attacking display is certainly a positive for De Zerbi’s men. Now, a visit to Old Trafford will really test this squad, and a victory could be the momentum that Spurs desperately need to turn their season around.

Manchester United vs Tottenham Injury News

Manchester United have several fitness concerns heading into Saturday's clash. Benjamin Šeško remains doubtful with a shin injury, while Patrick Dorgu, Noussair Mazraoui, and Matthijs de Ligt are also facing fitness tests. Marcus Rashford and Kobbie Mainoo could return, but Manuel Ugarte remains sidelined with a long-term knee injury.

Tottenham are without Xavi Simons and Wilson Odobert due to long-term knee injuries, while Dejan Kulusevski and Pedro Porro are also dealing with fitness issues. Micky van de Ven and Jan Paul van Hecke picked up injuries on international duty, although both could recover in time for Saturday.

Manchester United vs Tottenham Picks

Neither side is consistent, and Spurs haven’t proven anything so far this term. With United playing on home soil, I believe they have a significant edge, and their last game at the Theatre of Dreams against Spurs resulted in a convincing three points. I’ll back the hosts to replicate that performance and add to Tottenham’s misery.

Pick: Manchester United -139/TonyBet

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Quinn Allen is a sports writer from Vancouver, Canada. His expertise spans across many sports, but he tends to write mostly European soccer betting previews for BettingTop10 Canada. He’s been in the industry for seven years. Quinn loves to be active in his free time, whether it’s working out, walking, or playing soccer.