Premier League: Manchester United vs Brentford Odds, Analysis, & Picks

Quinn Allen
By: Quinn Allen
Soccer Picks
Photo courtesy of Ungry Young Man (Flickr), CC by 2.0

Photo courtesy of Ungry Young Man (Flickr), CC by 2.0

Manchester United will be looking to further secure their spot in the top four of the Premier League table on Monday, April 27, when they welcome Brentford to Old Trafford. The kickoff is scheduled for 3 p.m. ET. The Red Devils notched a massive victory last time out, beating Chelsea 1-0 at Stamford Bridge. The Bees, meanwhile, settled for a point in a scoreless draw with Fulham on home soil. Read below for the Manchester United vs Brentford picks.

Highlights

  • Manchester United and Brentford clash on Monday
  • The Red Devils are a -117 favorite
  • Keep reading for the odds, preview, and picks

Odds courtesy of TonyBet.

Manchester United vs Brentford Odds

United is a heavy -115 moneyline favorite at soccer betting sportsbooks. Brentford comes back at +295. A draw is always priced at +295, while the O/U is set at three goals.

The Bees have actually won back-to-back meetings with the Red Devils, but they were both in London. United has come out victorious in three straight matches against Brentford at Old Trafford.

Manchester United vs Brentford Analysis

The Red Devils truly looked lost earlier this season, but the arrival of Michael Carrick has done wonders. The club has every opportunity to bring Champions League football back to Old Trafford next season. They’re currently in third place with 58 points, compiling a 16-10-7 record. While a draw with Bournemouth and a defeat to Leeds prior to matchday 33 were far from ideal, United produced the goods against Chelsea last Saturday, adding to the Blues’ misery and putting themselves in a great position to qualify for the UCL with the three points.

Matheus Cunha’s first-half goal was all the visitors needed here, notching just their sixth victory of the campaign on the road. But, United’s form at the Theatre of Dreams has been absolutely phenomenal, posting a 10-3-3 record. Considering the loss to Leeds was on home soil, the Red Devils will be very poised to bounce back here against a Brentford side that has had their number over the last year.

The Bees’ summer transfer window prior to the 2025-26 campaign saw them lose their manager and two best players. Yet, they didn’t let it affect them, and Keith Andrews has guided this team to an impressive season. Brentford is only two points out of the top six, and if they do win here, the Bees would jump ahead of Brighton into sixth spot. This is an integral fixture for the London outfit.

However, winning games has been difficult for Brentford lately. They’ve drawn four straight Premier League matches, and their last win in the top flight was on March 28 against Burnley. While another point would still keep them in the mix for Europe, a win is the best-case scenario. But, as we know, Old Trafford isn’t an easy place to come out victorious, and the visitors have lost by a 2-1 scoreline in back-to-back games in Manchester.

Manchester United vs Brentford Injury News

Harry Maguire returns from suspension and is expected to slot back into central defense, with Lenny Yoro a possible partner after recent injury issues forced United into makeshift options. Matthijs de Ligt and Patrick Dorgu are both back in training, but they won’t feature.

Jordan Henderson remains sidelined but is nearing a return, while Rico Henry and Vitaly Janelt could still play again before the season ends. However, Fabio Carvalho, Jay Dasilva, and Antoni Milambo are all ruled out for the remainder of the campaign.

Manchester United vs Brentford Picks

It’s hard to ignore United’s form at home, and Brentford has failed to find the back of the net in two of their last three matches. I’ll take the Red Devils to secure a vital home victory on Monday.

Pick: Manchester United -115/TonyBet

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Quinn Allen is a sports writer from Vancouver, Canada. His expertise spans across many sports, but he tends to write mostly European soccer betting previews for BettingTop10 Canada. He’s been in the industry for seven years. Quinn loves to be active in his free time, whether it’s working out, walking, or playing soccer.