NFL Week 2 Player Prop Best Bets & Betting Odds

Alex Murray
By: Alex Murray
NFL Picks
NFL Week 2 Player Prop Best Bets & Betting Odds

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We didn’t make out so well with our player prop best bets in Week 1. The Lions rode Jahmyr Gibbs until the cows came home as we expected. But Rico Dowdle got out-touched by Jaylen Warren in what turned out to be a close game, and the game script never really worked in Omarion Hampton’s favour against the Cardinals. Live and learn.

We’ve got a new batch for you this week, including a couple of running backs going up against a couple of run defences that really struggled in Week 1 and ol’ reliable at quarterback. Read on for our top three player prop best bets for Week 2 as well as the latest NFL betting odds!

2026 Player Props Best Bets Record: 1-2 (-0.82)
2025 Player Props Best Bets Record: 34-25 (+5.61)
All-Time Record: 87-60 (+17.40)

Highlights

  • Bucky Irving out-touched Kenny Gainwell in the Buccaneers backfield 15-6 in Week 1
  • The Broncos gave up 197 rushing yards to Chiefs running backs last week
  • Jacoby Brissett has thrown for 240+ yards in 11 of his past 13 starts dating back to 2025

NFL Week 2: Player Prop Best Bets and Betting Odds

All betting odds provided by Betway.

Bucky Irving, RB, Tampa Bay Buccaneers - Over 59.5 Rush Yards (-108) vs. Cleveland Browns

Bucky Irving and the Buccaneers didn’t have a great game in Week 1. But Irving did show that he’s clearly the top dog in the Tampa backfield, having out-touched Kenny Gainwell 15-6 despite playing a similar amount of snaps. Irving went for 45 rushing yards and 48 receiving yards on the day.

We don’t expect such a big gap every week, but against the Browns in Week 2, there should be enough to go around anyway.

Without Myles Garrett in the mix, Cleveland has lost their identity as a defensive powerhouse. The Jaguars manhandled this unit last week, posting 23 first downs, 360 yards, and 34 points during a rough afternoon.

More importantly for our purposes, they gave up 66 yards to Bhayshul Tuten and 55 more to his backups. The Jags’ running backs went for 121 total yards (eighth-most in Week 1) and averaged about 4.8 yards per carry.

It’s nothing against Tuten and company, but Irving and Gainwell are much better backs, so they should have an even better day. Not to mention that the Bucs will be at home after a tough Week 1 loss where they’ll be desperate to get up early and stay up.

Bhayshul Tuten, RB, Jacksonville Jaguars - Over 49.5 Rush Yards (-110) @ Denver Broncos

Speaking of Bhayshul Tuten, we like him to have another solid day against a Broncos team playing on a short week here after a Monday night blowout loss to the Chiefs. The biggest reason for that defeat was their inability to stop the run. They gave up 220 rush yards and 197 to running backs in Week 1, both second-most in the league.
 
Kenneth Walker III had a field day against Denver’s defence, which was previously thought to be one of the best in the NFL. Walker’s 173 yards on the ground would beg to differ, however. And on a short week, we doubt the Broncos will have time to plug up all those holes in their run defence.

As we mentioned earlier, Tuten had a solid day in Week 1, taking 15 carries for 66 yards. If he can match that in Week 2, we’re golden. He out-carried Chris Rodriguez and Ameer Abdullah 15-10, though Rodriguez did play nearly as many snaps as Tuten. With the way Denver’s defence looked in Week 1, Tuten should be able to hit the 50-yard mark for us no problem.

Jacoby Brissett, QB, Arizona Cardinals - Over 216.5 Pass Yards (-110) vs. Seattle Seahawks

He just keeps getting it done doesn’t he. And now, not only is he getting it done on the stat sheet, but Jacoby Brissett is winning some games. Well, one game at least. Arizona pulled off what could go down as one of the biggest upsets of the season over the Chargers in Week 1, and Brissett’s arm was a big part of that, as per usual.

Brissett tossed it 37 times for 277 yards, the 11th time in his 13 starts with the Cardinals he’s eclipsed the 240-yard mark in a game. And with his number so low at just 216.5 against the division-rival Seahawks, we like him a lot this week.

The Seahawks have an excellent defence, but Brissett is proving that he’s kind of matchup proof. He threw for 250+ against top 10 defences in Green Bay and Seattle last year, and he also threw for 249 yards against the Texans, who were the best defence in the NFL in 2025.

Unless the Cardinals somehow jump out to a massive lead and choose to sit on it, Brissett feels like a lock to hit this number in Week 2.

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Alex Murray has been a consistent presence on BettingTop10 since he joined the team in 2020 just after graduating from Ryerson University’s Sport Media program in 2019. He has written for publications including theScore, Sporting News, FanSided, FantasyPros, and more over his 6+ years in the field. Alex has also been a lifelong athlete and sports fan who has channeled that love into his entertaining writing style and shrewd betting strategies.