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UFC 331: Tsarukyan vs. Ruffy Predictions & Betting Odds

Alex Murray
By: Alex Murray
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UFC 331: Tsarukyan vs. Ruffy Predictions & Betting Odds

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The UFC returns to Los Angeles this weekend. Believe it or not, the promotion hasn’t been to the L.A. since 2018. The main card for UFC 331 gets underway at 9 p.m. ET on Saturday night at Crypto.com Arena, so make sure you remember to tune in an hour earlier than usual.

While the flyweight championship bout in the main event is stealing headlines, the co-main event should also be an exciting scrap. No. 2 lightweight Arman Tsarukyan and No. 10 Mauricio Ruffy are set to do battle in that penultimate matchup of UFC 331. Read on for our tale of the tape, UFC betting odds, and our best bet for the showdown!

Highlights

  • Arma Tsarukyan has won his last 5 fights
  • Mauricio Ruffy has bounced back with 2 straight wins after suffering the 2nd loss of his career in September 2025
  • Ruffy just fought three months ago on June 14 at UFC Freedom 250

UFC 331: Joshua Van vs. Alexandre Pantoja Flyweight Championship Main Event Bout - September 19 - 9 P.M. EDT

All odds provided by Powerplay.

Tale of the Tape:

CategoryArman TsarukyanMauricio Ruffy
Height5’7” (1.70 m)5’11” (1.80 m)
Weight155 lbs (70 kg)155 lbs (70 kg)
Reach72.5” (184 cm)75.0” (191 cm)
Age2930
NicknameBatmanN/A
Fighting StanceOrthodoxOrthodox
Significant Strikes Landed/Minute3.854.19
Strikes Absorbed/Minute1.803.83
Takedown Average3.260.00
Takedown Defense75 %87 %
Current RankingNo. 2No. 10
Fighting Out OfYerevan, ArmeniaSao Paulo, Brazil

Fight Analysis & Prediction

No. 2 Arman Tsarukyan vs. No. 10 Mauricio Ruffy Co-Main Event Betting Odds

FighterMoneylineSpreadRoundsWin by DecisionWin by KO/TKO/DQWin by SubmissionGo the Distance
Arman Tsarukyan-330-5.5 (-200)O2.5 (-115)+350+195+220Yes (+240)
Mauricio Ruffy+265+5.5 (+155)U2.5 (-115)+1,100+400+2,800No (-330)

Arman Tsarukyan hasn’t fought in the UFC since last November, but he’s been keeping busy with RAF grappling matches in the meantime. Tsarukyan is 10-2 in the UFC, and his only losses came in his promotional debut against Islam Makhachev and a questionable against Mateusz Gamrot in 2022.

Mauricio Ruffy is the next guy on Tsarukyan’s hit list, which already includes wins over division mainstays Beneil Dariush, Dan Hooker, and Charles Oliveira. Ruffy, meanwhile, has beaten a 40-year-old Michael Chandler and No. 12 lightweight Rafael Fiziev since getting his face cranked by Benoit Saint-Denis last September.

And that loss is one that sticks in our mind when we look at his matchup here with Tsarukyan. BSD is an excellent wrestler and submission artist, but those are also Tsarukyan’s strong points. BSD might be a more dangerous threat when it comes to submitting opponents, but the Armenian is arguably the better wrestler.

When Ruffy starts launching those kicks he loves, Tsarukyan’s going to be ready with the takedown. And we think he’s going to keep the Brazilian there for a large portion of the fight, eventually frustrating him so much that he falls into a Tsarukyan submission.

Best Bet: Arman Tsarukyan to Win via Submission (+220)

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Alex Murray has been a consistent presence on BettingTop10 since he joined the team in 2020 just after graduating from Ryerson University’s Sport Media program in 2019. He has written for publications including theScore, Sporting News, FanSided, FantasyPros, and more over his 6+ years in the field. Alex has also been a lifelong athlete and sports fan who has channeled that love into his entertaining writing style and shrewd betting strategies.

Alex Murray
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