2025 NFL Futures Betting Odds: Number 1 Overall Pick Favored To Throw Most INTs

Alex Murray
By: Alex Murray
Aug 02, 2025
NFL Picks
Photo by Wikimedia Commons, CC by 2.0

Photo by Wikimedia Commons, CC by 2.0

We’ve been delving deep into the mile-long list of NFL futures betting markets available for the 2025 season. This time around, we’re taking a look at a fun one: who will lead the league in interceptions thrown? Right now, the No. 1 overall pick, Tennessee’s Cam Ward, is the slight favorite, but this one seems wide open if the odds at Canadian sportsbooks are anything to go by.

A player can have a great season and still lead the league in picks; just look at Baker Mayfield last year and Super Bowl champ Matthew Stafford in 2021. This one is really all about opportunity: which team will pass the most? We break down the favorites and identify our top long shot value bet!

Highlights

  • Baker Mayfield has the same odds to lead the NFL in INTs (+900) as he does to lead in TDs
  • Three times since 2018 the QB who led the league in pass attempts also led in INTs
  • Only 4 rookies have led the league in INTs in the Super Bowl era

2025 NFL Most Regular Season Interceptions Thrown Futures Market: Breakdown & Value Picks - August 1

All odds provided by Betway.

2025 NFL Most Regular Season Interceptions Thrown Betting Odds

PlayerJuly 27 Odds
Cam Ward (TEN)+850
Baker Mayfield (TB)+900
Sam Darnold (SEA)+1,000
Matthew Stafford (LAR)+1,100
J.J. McCarthy (MIN)+1,200
Trevor Lawrence (JAX)+1,200
Dak Prescott (DAL)+1,400
Jordan Love (GB)+1,400
Michael Penix Jr. (ATL)+1,400
Brock Purdy (SF)+1,500
Drake Maye (NE)+1,500
Tyler Shough (NO)+1,600
Geno Smith (LV)+1,800
Jared Goff (DET)+1,800
Josh Allen (BUF)+2,000
Caleb Williams (CHI)+2,500
Patrick Mahomes (KC)+2,500

The Favorites

Cam Ward, Tennessee Titans (+850): Cam Ward is an interesting proposition because, A) he’s a rookie, and only three rookies since 1970 have led the league in INTs, but B) he also seems like he’s going to have a long leash that could allow him to rack up numbers across the board. Including interceptions.

However, Ward was pretty responsible with the football in college. He threw just 14 interceptions over his last two years. Compare that to two of the most recent rookie INT leaders and he looks pretty good: Peyton Manning threw 23, and DeShone Kizer threw 20. (Trevor Lawrence and Terry Bradshaw were the other two) Ward will likely play all 17 barring injury, but we think he’ll play it safe enough to steer far clear of this dubious honor.

Baker Mayfield, Tampa Bay Buccaneers (+900): He tied for the league lead last year with Kirk Cousins, who played only 14 games before he was benched. So Baker Mayfield only kind of deserved it last year. And despite how much we like him this season, we can’t argue with the odds he’s getting here from betting sites either. He’s a gun-slinger.

And sometimes gun-slingers miss—but not when they have such a glut of clear targets. With so many talented receivers, it’s going to be hard for him to throw interceptions like he did last year. And last year he threw 16 to lead the league, the second-lowest league-leading figure in NFL history. Pass.

Sam Darnold, Seattle Seahawks (+1,000): There was all the news about how Sam Darnold’s big Seattle contract not quite being what it seems.. Which was followed by their drafting of exciting Alabama QB Jalen Milroe in the third round of the draft.. We’re not so sure Sam Darnold has the leash required to lead the league in this department.

Matthew Stafford, Los Angeles Rams (+1,100): People forget, but in 2021, when he led the Rams on that magical Super Bowl run, Matthew Stafford led the NFL with 17 interceptions. He’s even thrown 20 in a season before. We’re not quite sure why, but we have a sneaking suspicion that Stafford is going to be throwing the ball a lot this year for the Rams. Though he wouldn’t be our first choice.

Long Shot Value Bet

  • Caleb Williams, Chicago Bears (+2,500): The No. 1 pick last year was third in INT rate—but he was also seventh in pass attempts. We think with Ben Johnson in town, Caleb Williams is going to let loose more. And that’s going to mean more success and bigger numbers, but also more turnovers as he takes more chances and goes off the cuff more often (as he loves to do). With odds like this, a dart throw is a no-brainer on a hero ball guy like Williams in a pass-happy offense like Johnson’s. This would be our favorite bet on the board.
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Alex is a recent graduate of Ryerson's Sport Media program in 2019 and has been contributing to BettingTop10 since 2020. He has worked in the field of sports and sports betting for several years, including writing for theScore and daily fantasy sports website FantasyPros as one of their lead NBA news writers. A dedicated sports fan and experienced sports bettor, Alex has the knowledge to provide you with the best betting advice and the sneakiest props no matter what the sport may be.