Premier League: Crystal Palace vs Manchester City Odds, Analysis, & Picks

Photo courtesy of ajay_suresh (Flickr), CC by 2.0
Crystal Palace welcome Manchester City to Selhurst Park on Friday as both clubs play their second match of the 2026-27 Premier League campaign. The Eagles are looking to bounce back after a 2-0 defeat to Everton on Matchday 1, while Enzo Maresca’s Cityzens opened their season with a dramatic 2-1 victory over Bournemouth thanks to a late Josko Gvardiol winner. With Palace searching for their first points and City looking to build early momentum, Friday’s clash should be an intriguing affair. Read below for the Crystal Palace vs Manchester City picks.
Highlights
- Crystal Palace and Manchester City clash on Friday at Selhurst Park
- Both clubs head into their second match of the Premier League campaign
- Keep reading for the odds, preview, and picks
Odds courtesy of TonyBet.
Crystal Palace vs Manchester City Odds
| Moneyline | Crystal Palace +420 | Man City -159 |
| Total | Ov 3 (+106) | Un 3 (-127) |
Unsurprisingly, Man City is a clear -159 moneyline favorite at soccer betting sites. Palace, meanwhile, sits as a +420 home underdog. A draw is priced at +320 odds.
Since losing to the Eagles in the 2025 FA Cup final, the Cityzens have won back-to-back meetings with the London side. They pulled off the double last term, outscoring Palace 6-0.
Crystal Palace vs Manchester City Analysis
There’s been a lot of change at Selhurst Park this summer, with Oliver Glasner leaving his post as manager and Pierre Sage taking over. The loss of Maxence Lacroix to Chelsea also hurt the Eagles immensely, as the Frenchman was their top defender. Palace certainly missed Lacroix in the season opener, suffering a 2-0 defeat to Everton. While the visitors controlled 58% of the ball, they lacked the end product in the final third, notching just three shots on target.
The Toffees went up two goals to the good by the 54th minute, courtesy of Kiernan Dewsbury-Hall and Thierno Barry. It was a very disappointing result for the Eagles, who certainly had their fair share of opportunities. Now, they’re staring down a ridiculously tough clash with a City side that showed their quality in a come-from-behind win over Bournemouth.
A new era officially began on the blue side of Manchester last weekend, and it nearly started in defeat. Maresca’s men did not look promising for most of the fixture against the Cherries, sitting one goal down until the 84th minute. But it wasn’t Erling Haaland who saved the Sky Blues; it was a pair of defenders. Marc Guehi equalized with a thumping header from a set-piece before Josko Gvardiol played hero, calmly putting away a low shot into the left corner after VAR overturned the disallowed goal.
The fact that City needed a pair of defenders to provide the goals rather than their attackers is somewhat concerning, but three points is three points, and City will hope to build on that. The club did some phenomenal business this week as well, signing Moroccan wonderkid Ayyoub Bouaddi from French club Lille. He’ll be a massive addition in the middle of the park, but it’s unlikely he debuts this weekend after the deal was just completed on Thursday.
Crystal Palace vs Manchester City Injury News
Crystal Palace will be without Ismaïla Sarr and Chadi Riad for Friday’s clash. Sarr remains sidelined with a groin injury, while Riad suffered a knee problem during the 2-0 defeat to Everton on Matchday 1 and is seeking specialist advice. Sage did not provide a timetable for the defender’s return.
Manchester City are in much better shape from a fitness standpoint, although Jérémy Doku remains sidelined with a calf injury and is not expected back until September. The Sky Blues otherwise have no significant fresh injury concerns following their 2-1 victory over Bournemouth on Sunday.
Crystal Palace vs Manchester City Picks
Historically, this has been a high-scoring affair. The Over 2.5 goals cashed in both meetings in 2025-26, and it’s also hit in six of the previous seven clashes. With Palace looking vulnerable at the back and City not looking their best so far, I like another fixture full of goals. But expect most of the scoring to come from the visitors.
Quinn Allen is a sports writer from Vancouver, Canada. His expertise spans across many sports, but he tends to write mostly European soccer betting previews for BettingTop10 Canada. He’s been in the industry for seven years. Quinn loves to be active in his free time, whether it’s working out, walking, or playing soccer.

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