NFL 2025 Thanksgiving Thursday Tripleheader Game Picks & Odds

Alex Murray
By: Alex Murray
NFL Picks
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This season, the NFL has scheduled a really interesting slate for this season’s Thanksgiving Thursday NFL tripleheader. The Detroit Lions and Dallas Cowboys, as always, will host the first two games, with the Green Bay Packers and Kansas City Chiefs, respectively, serving as opponents. Then we get an exciting AFC North clash between the Cincinnati Bengals and Baltimore Ravens for the night cap.

Get your turkey bibs on because we’re about to feast on this slate with our best bets for each of these matchups! Read on for our picks and analysis as well as the top NFL betting odds in Canada!

Highlights

  • The Lions have won 3 of the last 4 meetings with the Packers in Detroit
  • Patrick Mahomes is 6-2 on Thursday in his career
  • Cincinnati has lost just 1 of the last 9 matchups with Baltimore by more than 7 points

NFL Week 13 Thanksgiving Thursday Triple Header - November 27

All odds provided by Betway.

Green Bay Packers (7-3-1) @ Detroit Lions (7-4) - 1PM E.T.

TeamMoneylinePoint SpreadOver/Under
Green Bay Packers+130+2.5 (+100)O48.5 (-105)
Detroit Lions-1542.5 (-120)U48.5 (-115)

The Lions escaped with a big win last week against the Giants, and that will likely have snapped them out of whatever funk they were in. That was a very close call. Dan Campbell will have these guys ready for this matchup. It could very well determine who wins the NFC North if the Bears fall away as most expect them to.

The Lions have won three of the last four and five of the last eight matchups between these two teams in Detroit. They have also never been swept by the Packers during the Dan Campbell era. Considering they lost to the Packers in Week 1, in embarrassing fashion might we add, that bodes well for a Lions ML bet here.

Detroit has shown that it’s a team that bounces back well from losses and holds a grudge. They’re going to be waiting to pounce on the Packers in this one. And it’s not like Green Bay has really shown themselves to be reliable. They are one of the most erratic clubs in football. As long as Jahmyr Gibbs gets enough run, the Lions should take care of business and get home early for turkey.

Best Bet: Detroit Lions Moneyline (-154)

Kansas City Chiefs (6-5) @ Dallas Cowboys (5-5-1) - 4:30PM E.T.

TeamMoneylinePoint SpreadOver/Under
Kansas City Chiefs-180-3.5 (+100)O52.5 (-110)
Dallas Cowboys+152+3.5 (-120)U52.5 (-110)

This is one of the most high profile matchups in recent Thanksgiving memory. America’s Team versus the Face of the League. The Cowboys play on Thanksgiving every year, and they’ve won their last three in a row—but they lost the three in a row before that.

The Chiefs, meanwhile, have not played on Thanksgiving since 2006. Surprising, but true. This will be Patrick Mahomes’ first Thanksgiving game, but we reckon he’ll be able to handle the size of the moment. Plus, this is really just a Thursday short turnaround week with a few extra festivities and cooked birds. Mahomes is 6-2 for his career on Thursdays, and we think that trend will hold here.

Both of these teams have clearly capable and talented offenses, but the Chiefs have a much tougher top five defense than the unit the Cowboys have been trotting out, which is 31st in points allowed. They both desperately need this game, but we like the Chiefs to find the small margins and stay alive in a heated AFC playoff race.

Best Bet: Kansas City Chiefs Moneyline (-180)

Cincinnati Bengals (3-8) @ Baltimore Ravens (6-5) - 8:20PM E.T.

TeamMoneylinePoint SpreadOver/Under
Cincinnati Bengals+270+7.0 (-110)O51.5 (-110)
Baltimore Ravens-335-7.0 (-110)U51.5 (-110)

What seemed like a completely dead game a few weeks ago is now a classic divisional rivalry match between Lamar Jackson—who returned to action a few weeks ago and has carried his team from worst to first in the division—and Joe Burrow—who is making his surprisingly early return to the lineup after nearly three months on the shelf. Fireworks, anyone?

Well, don’t count on it. There is the potential with those two guys, of course, but neither will be at full strength. Jackson is back from injury, but we’ve not seen him be his usual explosive self. There’s something still amiss. And Burrow will be managing the pain of his turf toe injury. He hasn’t actually moved past it.

Since 2021, the Bengals have won or lost by less than a score in every edition of this matchup—apart from the game where Burrow broke his wrist a few years ago. That’s eight of nine games either won by Cincy or finishing tight. The Bengals defense is awful, but we’re not sure the Ravens defense is really all that good either. And most betting sites are giving a whole TD on the spread in a high profile divisional game. It’s got underdog written all over it.

Best Bet: Cincinnati Bengals Alternative +7.5 Point Spread (-120)

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Alex Murray has been a consistent presence on BettingTop10 since he joined the team in 2020 just after graduating from Ryerson University’s Sport Media program in 2019. He has written for publications including theScore, Sporting News, FanSided, FantasyPros, and more over his 6+ years in the field. Alex has also been a lifelong athlete and sports fan who has channeled that love into his entertaining writing style and shrewd betting strategies.