NFL Pick 6: Week 3 6-Leg, 6-Point Teaser Parlay

Alex Murray
By: Alex Murray
Sep 26, 2025
NFL Picks
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We missed our six-leg six-point teaser parlay by one leg in Week 1, but we made good on it in Week 2, going six-for-six for a big win. We skipped Week 3, and that seems like it might have been lucky considering the shocking results we saw across the NFL. Betting apps were certainly happy. But that won’t happen every week, and we’re back here in Week 3 with what we think is another win on the teaser parlay.

2025 Pick 6 Teaser Parlay Record: 1-1 (+5.00)

2025 Pick 6 Teaser Picks: 11-1

Highlights

  • The Buccaneers have won their last two meetings with the Eagles by double-digits
  • Houston’s season is on the line in a must-win home game against Tennessee
  • Baltimore will show just how bad the Chiefs are right now

NFL Week 4 Pick 6: Week 1 6-Leg, 6-Point Teaser Parlay

All odds provided by Sports Interaction.

  • (H) Tampa Bay Buccaneers +3.5 Spread → +9.5
  • (H) Detroit Lions -9.5 Spread → -3.5
  • (H) Houston Texans -7.5 Spread → -1.5
  • (A) Los Angeles Chargers -6.5 Spread → -0.5
  • (A) Indianapolis Colts +3.5 Spread → +9.5
  • (A) Baltimore Ravens -2.5 Spread → +3.5
  • Parlay Odds: +600

Philadelphia Eagles @ Tampa Bay Buccaneers (+3.5) - 1PM

The Buccaneers beat up on the Eagles in the 2023 playoffs, and they were one of just three teams to beat them last year too. And they didn’t just beat them either, they kind of dominated them in a 33-16 win. That sparked a 10-game winning streak for Philly. And it feels like the Eagles are once again in need of a jump start, and Baker Mayfield and the Bucs will be happy to oblige. The Eagles have struggled to pass the ball, and Tampa Bay’s tough run defense will force them to do just that. Chris Godwin returns to offset the loss of Mike Evans for the Bucs as well.

Teaser Pick: Buccaneers (+9.5)

Cleveland Browns @ Detroit Lions (-9.5) - 1PM

The Cleveland Browns are not going to win a lot of games this season. They’re certainly not going to win two in a row. And especially not against two of the best teams in the NFC. The Packers were shocked by these Browns on the road, but the Lions have looked the better team since losing to Green Bay in Week 1. Detroit has the blocking to slow that Cleveland pass rush that causes so many issues. They will learn from their rival’s mistakes and put a beatdown on one of the worst teams in football.

Teaser Pick: Lions (-3.5)

Tennessee Titans @ Houston Texans (-7.5) - 1PM

It’s really now or never for the Texans. They were expected to win the AFC South, but now they are 0-3 and the Colts are 3-0. That’s a lot of ground to make up. Only one team in NFL history has ever made the playoffs after an 0-4 start, so it’s all on the line here. They will play with desperation at home against a Titans team that doesn’t seem interested in winning right now anyway.

Teaser Pick: Texans (-1.5)

Los Angeles Chargers (-6.5) @ New York Giants  - 1PM

Jaxson Dart getting his first career start here against the Chargers is not ideal. This is a tough and physical defense with a lot of playmakers flying around to confuse the youngster. We know they’re on the road, but we think L.A.’s defense could make this an ugly one for Dart and the Giants at MetLife.

Teaser Pick: Chargers (-0.5)

Indianapolis Colts (+3.5) @ Los Angeles Rams - 4:05PM

Are Daniel Jones and the Colts for real? We’re likely to find out when they hit the road here against the Rams. Or so most have said. We think Indy is already stamped as a solid team after putting up points against that tough Broncos defense a couple of weeks ago. They might lose this one, but not by double digits.

Teaser Pick: Colts (+9.5)

Baltimore Ravens (-2.5) @ Kansas City Chiefs - 4:25PM

Lamar Jackson is just 1-4 against Patrick Mahomes in the regular season, but we think he bucks that trend this week. The Chiefs have looked positively atrocious through three weeks, and the Ravens are by far the best 1-2 team in the league. The Ravens offense is going to make quick work of the Chiefs defense, and we foresee a big day from Derrick Henry.

Teaser Pick: Ravens (+3.5)/Sports Interaction

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Alex is a recent graduate of Ryerson's Sport Media program in 2019 and has been contributing to BettingTop10 since 2020. He has worked in the field of sports and sports betting for several years, including writing for theScore and daily fantasy sports website FantasyPros as one of their lead NBA news writers. A dedicated sports fan and experienced sports bettor, Alex has the knowledge to provide you with the best betting advice and the sneakiest props no matter what the sport may be.