NFL Week 7 Early 1PM Slate Betting Picks, Odds, & Best Bets

Alex Murray
By: Alex Murray
Oct 18, 2025
NFL Picks
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The Colts failing to cover at home last week against the Cardinals cost us our second perfect card of the season, but we still had a great week. We’ll look to continue that trend here in Week 7 with a tight six-game slate scheduled for the early afternoon 1PM ET window on Sunday. Let’s dive into our best bets for each game!

2025 1PM Slate Best Bet Record: 28-18 (+2.12)

Note: None of our best bets feature odds shorter than -200.

Highlights

  • Minnesota has allowed back-to-back 99+ yard rushers
  • The Saints are 1-4 ATS as underdogs this season
  • Miami is allowing an NFL-worst 168.5 rushing yards per game

NFL Week 7 Early Sunday 1PM Betting Picks & Odds - October 19

All odds provided by Sports Interaction.

Philadelphia Eagles @ Minnesota Vikings - 1PM

TeamMoneylinePoint SpreadTotal (Over/Under)
Philadelphia Eagles-124-2.5 (-110)O43.5 (-110)
Minnesota Vikings+106+2.5 (-110)U43.5 (-110)

Brian Flores has the Vikings defense playing brilliantly. They are probably the most unpredictable unit on that side of the ball right now. But they do have one weakness, and we believe the Eagles are primed to take advantage of it: run defense.

They are allowing over 138 rushing yards per game this season, ninth-most. Minnesota was gashed in their last two games by the likes of Quinshon Judkins (110 rush yards) and Kenneth Gainwell (99), and let’s not forget Bijan Robinson’s 140+ yard effort against the Viks in Week 2. Saquon Barkley hasn’t had 70+ yards since Week 2, but we think this is the game where he breaks out.

Best Bet: Saquon Barkley To Rush For 70+ Yards (-150)

Las Vegas Raiders @ Kansas City Chiefs - 1PM

TeamMoneylinePoint SpreadTotal (Over/Under)
Las Vegas Raiders+530+12.5 (-110)O45.5 (-110)
Kansas City Chiefs-750-12.5 (-110)U45.5 (-110)

The Raiders have been playing the Chiefs as tough as anyone over the last few seasons, despite the fact that they’ve been generally awful otherwise. They covered two double-digit spreads like this against K.C. last year, and they won at Arrowhead outright in two of the four seasons before that. After their big win over Detroit, betting apps are a little too bullish on the Chiefs here. And we think K.C. themselves might be too.

Best Bet: Las Vegas Raiders +12.5 Point Spread (-110)

New Orleans Saints @ Chicago Bears - 1PM

TeamMoneylinePoint SpreadTotal (Over/Under)
New Orleans Saints+198+4.5 (-110)O46.5 (-110)
Chicago Bears-240-4.5 (-110)U46.5 (-110)

This could be a blowout for the Bears. The Saints have “stayed in games”, but they’re still 1-4 ATS as an underdog this season, and they’ve lost by six or more four times already. The Bears are riding a three-game winning streak, and their most recent conquest of the Commanders was impressive. The fact that they can now run the ball with D’Andre Swift pushed us over the edge on Chicago here.

Best Bet: Chicago Bears -4.5 Point Spread (-110)

Miami Dolphins @ Cleveland Browns - 1PM

TeamMoneylinePoint SpreadTotal (Over/Under)
Miami Dolphins+126+2.5 (-110)O35.5 (-110)
Cleveland Browns-148-2.5 (-110)U35.5 (-110)

Playing the Miami Dolphins is a running back’s dream right now. They’re allowing an NFL-high 168.5 rushing yards per game as well as 5.6 yards per carry, which is third-most. Cleveland can’t throw the ball to save their life anyway, so it’s Quinshon Judkins time. The rookie had a streak of 80+ yard games from Week 3 to 5, culminating in a 110-yard performance against Minnesota two weeks ago. He could have another career day at home against the hapless Fins.

Best Bet: Quinshon Judkins To Rush For 90+ Yards (-138)

Carolina Panthers @ New York Jets - 1PM

TeamMoneylinePoint SpreadTotal (Over/Under)
Carolina Panthers-118-1.5 (-110)O41.5 (-110)
New York Jets+100+1.5 (-110)U41.5 (-110)

We want to finally trust the Panthers as a favorite here, but they are 1-15 on the road under Bryce Young. Not good. But, we can’t take ourselves seriously betting on the Jets right now either. So: both of these teams have allowed 24+ points in five of six games. Both offenses have put up 20+ four times. And both are bottom 10 in points allowed. We’ll take the over here.

Best Bet: Game Total Over 41.5 Points (-110)

New England Patriots @ Tennessee Titans - 1PM

TeamMoneylinePoint SpreadTotal (Over/Under)
New England Patriots-300-6.5 (-110)O42.5 (-110)
Tennessee Titans+245+6.5 (-110)U42.5 (-110)

The Pats want a win for first-year HC Mike Vrabel over the franchise that fired him two years ago. The Titans want a win for their newly promoted interim coach Mike McCoy. Whichever narrative you like better, we’ll take the team with the better coaching staff, the better QB, the better defense, and the better record. Tennessee has lost 10 straight home games against the spread, if you needed further motivation.

Best Bet: New England Patriots -6.5 Point Spread (-110)

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Alex is a recent graduate of Ryerson's Sport Media program in 2019 and has been contributing to BettingTop10 since 2020. He has worked in the field of sports and sports betting for several years, including writing for theScore and daily fantasy sports website FantasyPros as one of their lead NBA news writers. A dedicated sports fan and experienced sports bettor, Alex has the knowledge to provide you with the best betting advice and the sneakiest props no matter what the sport may be.