MLB: Dodgers vs Cubs Odds, Analysis, & Picks

Photo courtesy of Wally Gobetz (Flickr), CC by 2.0
The first-place Los Angeles Dodgers hit the road on Monday evening to begin a three-game set with the Chicago Cubs at Wrigley Field. The first pitch is scheduled for 8:05 p.m. ET. LA will send Justin Wrobleski, arguably their best starter this season, to the hill for the series opener. Chicago counters with a lefty as well in veteran Matthew Boyd. Read more for our Dodgers vs Cubs picks.
Highlights
- The Dodgers face the Cubs on Monday
- The Dodgers face the Cubs on Monday
- Keep reading for the odds, preview, and picks
Odds courtesy of TonyBet.
Dodgers vs Cubs Odds
| Moneyline | Dodgers -132 | Cubs +104 |
| Total Runs | Ov 8.5 (-118) | Un 8.5 (-109) |
The Dodgers head into the series opener as a clear -132 moneyline favorite at MLB betting sites. The Cubbies are priced at +104. The total is set at a relatively modest 8.5 runs.
This is the second series of the season between LA and Chicago, with the defending World Series champions taking two out of three from the Cubs in April.
Dodgers vs Cubs Analysis
The Dodgers are once again a force in 2026, and a clear favorite to win it all again for the third straight year. LA is 10 games clear at the top of the National League West, and to be honest, it’s hard to imagine anyone stopping them from making another run to the Fall Classic. LA just beefed up their rotation even more on Saturday, pulling off a blockbuster trade for Cy Young winner Tarik Skubal, giving them another elite arm.
While they have lost two in a row as of writing ahead of Sunday’s finale against the Boston Red Sox, this is a team that is incredibly well-rounded. The Dodgers are top-two in nearly every offensive category, ranking first in average, OBP, and OPS. They’re also second in runs scored. On the hill, LA has a 3.60 team ERA, and Wrobleski has done his part. The southpaw owns a stellar 11-2 record and 2.88 ERA across 18 appearances. With Tyler Glasnow and Blake Snell having missed significant time, Wrobleski has taken advantage of his opportunity.
The Cubbies are also a team to watch, although they’re not as dominant as Los Angeles. Craig Counsell’s ball club is in second place in the National League Central with a 63-48 record, sitting 6.5 games back of the Milwaukee Brewers. Unless they can catch the Brew Crew, the Wild Card will likely be Chicago’s path to the playoffs. They currently sit first in the NL Wild Card race.
Offense has been a clear strength for the Cubs. They’re second in runs scored, fourth in OPS, and 10th in team average. Pete Crow-Armstrong and Seiya Suzuki have led the way, but the likes of Alex Bregman, Dansby Swanson, and Michael Busch have contributed as well. Boyd will be looking to keep up his recent success on Monday, having allowed just two earned runs across his last three starts. The left-hander has posted a 6-1 record and 3.41 ERA across 12 outings.
Dodgers vs Cubs betting trends
- The Cubs are 4-0 in their last four games vs. National League West.
- The Under is 5-1 in the Cubs’ last six games overall.
- The Over is 5-1 in the Cubs' last 6 games vs. a team with a winning % above .600.
- Over is 8-2 in the Dodgers’ last 10 during Game 1 of a series.
Dodgers vs Cubs Picks
Wrobleski is coming off a tough outing where he allowed four home runs, and he’s had issues at times on the road this season. Chicago also enters this game in solid offensive form. I’ll take the Cubbies as a home underdog.
Quinn Allen is a sports writer from Vancouver, Canada. His expertise spans across many sports, but he tends to write mostly European soccer betting previews for BettingTop10 Canada. He’s been in the industry for seven years. Quinn loves to be active in his free time, whether it’s working out, walking, or playing soccer.

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