Super Bowl 60 Game Picks: Spread, Over/Under, Betting Odds

Alex Murray
By: Alex Murray
NFL Picks
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The wait is finally over and the Big Game has nearly arrived. Super Bowl 60 will kick off on the evening of Sunday, February 8 as it wraps up what was a whacky and wild 2025 NFL campaign. To underline that last point, just look at this Super Bowl matchup between the unheralded New England Patriots and Seattle Seahawks.

The Seahawks are significant favorites here, but will they play up to expectations? Or will Maye and the Patriots have a little something up their sleeves for this seemingly indestructible Seahawks team? Read on for our game picks from the top Super Bowl sportsbooks.

Highlights

  • The Seahawks’ -4.5 point spread is the largest for a Super Bowl since 2015
  • The 2021 Rams are the only favorites to win the Super Bowl in the last 5 years
  • New England’s final 14 straight regular season games all topped 40 points

Super Bowl 60 Patriots vs. Seahawks Game Picks: Spread, Over/Under, Betting Odds

All betting odds provided by Betway.

TeamMoneylinePoint SpreadOver/Under
New England Patriots-235+4.5 (-110)O45.5 (-110)
Seattle Seahawks+194-4.5 (-110)U45.5 (-110)

Patriots vs. Seahawks Moneyline/Point Spread Prediction

From the AFC, the New England Patriots emerged through an admittedly weak conference with a first-year head coach and a second-year QB at the helm. In the NFC, the No. 1 seeded Seattle Seahawks did what they were supposed to do in reaching the Super Bowl.

But they too bring a relative lack of experience to the party with head coach Mike Macdonald wrapping up just his second year as an NFL head coach and his QB, Sam Darnold, completing his first season in the Pacific Northwest. Not to mention Darnold’s individual history to boot.

Darnold has grown with each stop he has made in the NFL. He struggled in New York, learned as a backup for a couple of years, then got another starting job for the Vikings in 2024. He balled out, winning 13 games. But that was all clouded by shocking performances from Darnold that cost Minnesota the division crown and a deep playoff run in his final two games in the purple and gold.

However, Darnold has gotten over those yips he had in Minnesota and the ghosts he saw in New York. He proved that he is the real deal by outduelling the likely MVP (Matt Stafford) in the NFC Championship. Darnold can sit back and earn a playoff win with just 124 passing yards like he did in the Divisional. But when he needs to, he can go for 346 yards and three TDs like he did against L.A.

We have not seen the same from Drake Maye throughout these playoffs. The second-year QB is really looking his age over the last few weeks. With these teams both boasting strong defenses and coaching staffs, the difference is likely to be the QB, and Darnold has the edge here. We’re not touching the spread, however, with the last five Super Bowl favorites failing to cover.

Best Bet: Seattle Seahawks Moneyline (-235)

Patriots vs. Seahawks Over/Under Prediction

This is shaping up to be a top notch defensive matchup. The Seahawks folded somewhat in the face of the Rams’ attack, but Drake Maye’s group isn’t nearly as good as L.A.’s was. Meanwhile, the Patriots defense has not put one foot wrong yet this postseason. They have allowed just 26 points across three combined playoff games.

However, that was against a Chargers team without an offensive line, C.J. Stroud in saboteur mode, and a backup QB in a snowstorm in Denver. Darnold, Jaxon Smith-Njigba, and Kenneth Walker will pose a completely different challenge. Since 2012, only two of the last 14 Super Bowls have gone under 40 points. We’re buying a few points down here, but this feels proper safe.

Best Bet: Alternative Game Total Points Over 40.5 (-225)

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Alex Murray has been a consistent presence on BettingTop10 since he joined the team in 2020 just after graduating from Ryerson University’s Sport Media program in 2019. He has written for publications including theScore, Sporting News, FanSided, FantasyPros, and more over his 6+ years in the field. Alex has also been a lifelong athlete and sports fan who has channeled that love into his entertaining writing style and shrewd betting strategies.