Green Bay Packers vs Minnesota Vikings: NFL Predictions, Odds & Picks | Week 10

Sunday, November 15, 2026 · 1:00 PM ET · Lambeau Field, Green Bay, WI · FOX

Odds courtesy of Bet365, correct at time of writing and subject to change.

Minnesota arrives at Lambeau Field mid quarterback shake-up. Kyler Murray sat out the Week 9 loss to Buffalo with a hamstring injury, Carson Wentz struggled badly in relief, and the Vikings made a quarterback trade on deadline day, bringing back Kirk Cousins, who played for the team from 2018-2023. While it has not been formally announced as of Thursday morning, Cousins is expected to start this Sunday.

The Vikings have lost two in a row while Green Bay has won two in a row and is coming off an impressive blowout win over the New England Patriots. This NFC North rematch of September's 39-22 Minnesota win looks very different three months later, and that form gap drives Sunday's NFL picks Week 10 slate.

Green Bay Packers -3.5: -106

I'm backing Green Bay to cover here. The Packers average 23.7 ppg while allowing 21.6 ppg, and have won four of five games. Minnesota's defence is the real strength of the team, but it now faces a Vikings offence that is likely starting a QB that came to the team this week. The Packers have totaled 72 points in their last two games and while they face the league’s top defense with the QB situation a little dicey for Minnesota, I like Green Bay at home only giving 3.5 points.

Odds from Bet365 and Sports Interaction, correct at time of writing and subject to change.

The Green Bay side

Jordan Love anchors the Packers offence, fresh off a  45-27 win over New England that pushed Green Bay to 6-3. Four of Green Bay's six wins have come against losing teams, but a 31-7 beatdown of a now 7-2 Chicago squad tells me the most about this roster heading into Sunday. While the run game ranks dead last in the league the passing offense ranks second and the team is balanced ranking 12th in scoring and 11th in scoring defence. 

The Minnesota side

Minnesota is still 6-2, a record that keeps the Vikings in the thick of a crowded NFC North race despite a broken quarterback room. Murray was out with a hamstring injury for last week's 23-6 loss to Buffalo, Wentz started and struggled badly, which is why Cousins was brought back. 

Four of the Vikings' six wins have come against teams a combined 9-25, tempering this record against a Green Bay team in form. However, they have the league’s best defense and it remains to be seen if Cousins will be the answer. 

Bet365	Sports Interaction
Packers -3.5	Packers Moneyline
-106	-175
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Bet Now	Bet Now

Bet365 and Sports Interaction odds, correct at time of writing and subject to change.

Bet365's -182 price on Green Bay implies a de-vigged win probability of about 62% to Minnesota's 38%. My number sits a little above that, 65% to 35%, not because Minnesota's defence is overrated, but because the Vikings are asking a quarterback with few practice reps, to beat a complete team on the road. Minnesota's top-ranked defence, allowing just 14.5 ppg, is exactly why I'm not pushing that number any higher than 65%.

I'm backing Green Bay to win this one 24-13. That leans on two things I haven't covered: Minnesota's offence has scored a combined 21 points across its last two games, and a cold November trip to Lambeau is a tough first start for a reshuffled quarterback room. A 37-point total finishes under both Bet365's 42.5 line and Sports Interaction's 42.0 line, so the Under is my total pick alongside Green Bay covering the -3.5 spread in their house.