NFL Week 5 Player Prop Best Bets, Picks, & Odds

Alex Murray
By: Alex Murray
Oct 05, 2025
NFL Picks
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After a few rough weeks with our player props bets, we finally had a positive card in Week 4. And it’s no surprise. We rely on data from the current season to make accurate bet predictions, and now we finally have a full month’s worth to go on.

We hit two thirds of these bets last year, so we foresee a return to the mean very shortly. Hop on. We missed out on a perfect 4-for-4 card last week by just three Hunter Henry yards. We’ve got the best betting odds in Canada for Week 5, and we’ll look to be those three yards better with our player prop best bets this time around.

2025 Player Props Best Bet Record: 6-10 (-4.54)

Highlights

  • Tennessee has given up the third-most rushing yards to RBs this season
  • Tommy Tremble played over 75 percent of the Panthers’ snaps last week
  • Darren Waller has 27 yards on just 16 offensive snaps in his Week 4 debut

NFL Week 5 Player Prop Best Bets & Odds

All odds provided by Sports Interaction.

Michael Carter, RB, ARI - Over 42.5 Rushing Yards (-110) vs. TEN

The Cardinals are really getting down to the bare bones of their running back room. But as we like to say: all of these guys are pros. Arizona is now left with Michael Carter and Emari Demercado in the backfield, and the split seems clear: Carter is the runner, Demercado is the guy in passing situations.

And since they’re hosting the Titans, we expect the former to be getting a lot more work. Tennessee has allowed the third-most rushing yards to RBs (117.5) and opponents have run on them with the sixth-highest frequency. They’re 0-4 for a reason. You may not know the name Michael Carter, but it’s going to be a ground game in the desert.

Woody Marks, RB, HOU - Over 52.5 Yards (-110) @ BAL

You didn’t know this guy’s name last week, but that’s fine, because we knew it and we nailed our bet on Woody Marks. We did our homework ladies and gentlemen, that’s why they pay us the medium-to-small bucks over here. He went for 69 yards on a 27.5 line last week, and it seems sports betting sites have smartened up. But not enough.

His 52.5 line this week is almost double what his Week 4 line was, but against this Ravens defense, we still believe it’s too small. Marks has pretty clearly taken over the backfield from Nick Chubb. On top of that, the Ravens are without a handful of their top defensive linemen, as well as their best run-stopping linebacker in Roquan Smith. They give up the fifth-most rushing yards per game to RBs (116.0). And Houston certainly won’t be playing catch up against the Cooper Rush-led Ravens offense, that’s for sure.

Tommy Tremble, TE, CAR - Over 25.5 Receiving Yards vs. MIA

We’ve got a couple of bets for this exceedingly mediocre matchup in North Carolina. First off, Tommy Tremble will be getting all the TE snaps he can handle again this week with Ja’Tavion Sanders out again. It was just Tremble last week, and he racked up five catches for 42 yards and a TD on eight targets.

Miami has allowed an opposing tight end to eclipse 60 yards in three of four games this year. Throw in the fact that the Dolphins have given up 302 receiving yards to TEs this season—most in the NFL—and you’ve got a recipe for success for us and Mr. Tremble.

Darren Waller, TE, MIA - Over 29.5 Receiving Yards @ CAR

We go across to the opposite sideline in Charlotte for our final player prop best bet of the week. After over a year away from the game, Darren Waller returned for the Dolphins last week and had three catches for 27 yards and two scores on four targets. And he played just 16 snaps.

He will play more this week, and with Tyreek Hill out, he can expect exponentially more looks as well. He’s about to become a huge part of this offense, and it doesn’t hurt that this matchup comes against a Panthers defense allowing the second-most receiving yards (71.3) to TEs this season.

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Alex Murray has been a consistent presence on BettingTop10 since he joined the team in 2020 just after graduating from Ryerson University’s Sport Media program in 2019. He has written for publications including theScore, Sporting News, FanSided, FantasyPros, and more over his 6+ years in the field. Alex has also been a lifelong athlete and sports fan who has channeled that love into his entertaining writing style and shrewd betting strategies.