Premier League: Tottenham vs Arsenal Odds, Analysis, & Picks

Photo courtesy of Paul Hudson (Flickr), CC by 2.0
Bitter rivals go to battle on Sunday, February 22, at Tottenham Hotspur Stadium as Tottenham welcomes league leaders Arsenal to North London. The kick-off is scheduled for 11:30 a.m. ET. Spurs have lost back-to-back Premier League games, and barely sit above the relegation zone at the moment. The Gunners are still in first place, but they slipped up mid-week in a 2-2 draw with Wolves. Read on for the Tottenham vs Arsenal picks.
Highlights
- It’s Tottenham vs Arsenal on Sunday
- The Gunnners are a clear -173 favorite
- Keep reading for the odds, preview, and picks
Odds courtesy of TonyBet.
Tottenham vs Arsenal Odds
| Moneyline | Tottenham +500 | Arsenal -173 |
| Total Goals | Ov 2.5 (-125) | Un 2.5 (+106) |
Arsenal heads into the North London derby as a heavy -173 moneyline favorite at soccer betting sportsbooks. Tottenham returns as a +500 underdog, giving them just a 16.67% chance of coming out with a victory.
The reverse fixture at the Emirates in November ended 4-1 Arsenal. In fact, they’ve won four straight against Spurs.
Tottenham vs Arsenal Analysis
It’s been an incredibly poor campaign for Tottenham, who recently sacked Thomas Frank after just half a season in charge. Igor Tudor, who was in the Juventus dugout in 2025, has taken over and will be looking to help the Lilywhites turn around their fortunes. He has a tall task ahead of him on Sunday, though, as Spurs haven’t beaten Arsenal since May of 2022.
The club is in very poor form, notching just one victory in their last nine Premier League appearances. Tottenham currently sits in 16th with a 7-8-11 record, just five points above safety. Their last win in England was at the end of December. While they’ve had a handful of draws since then, Spurs have lost back-to-back games to Newcastle and Manchester United. On a more positive note, the North Londoners are through to the Round of 16 of the Champions League – a lone bright spot so far in 2025-26.
Arsenal remains the favorite to lift the Premier League title, but their recent inconsistencies have given Manchester City a clear chance to catch them. They’ve drawn two straight games against Brentford and Wolves, two clubs the Gunners should be comfortably beating. Mikel Arteta’s side looked on their way to three points against Wolves on Wednesday, but Tom Edozie bagged a late equalizer for the hosts.
Arsenal now sits just five points above City in the title race, and while the Sky Blues have looked shaky at times, the Gunners cannot afford to have another inconsistent performance. The ultimate prize remains very clearly in sight, though, and Arteta’s squad is also the only side in the Champions League to go a perfect 8-0-0 in the group stages. They await their Round of 16 opponent, and winning the Premier League and UCL is a serious possibility.
Tottenham vs Arsenal Injury News
Wilson Odobert has been ruled out for the season after rupturing his ACL against Newcastle, adding to a lengthy Spurs absentee list that includes Pedro Porro (thigh), Dejan Kulusevski (knee), James Maddison (ACL), Mohammed Kudus (thigh), Kevin Danso (ankle), Destiny Udogie (thigh), Lucas Bergvall (ankle), Ben Davies (ankle) and Rodrigo Bentancur (thigh). Cristian Romero will also serve the second game of his four-match suspension. Richarlison is still sidelined, too.
Arsenal are in a far stronger position fitness-wise and could welcome back several key figures. Martin Odegaard (knee), Kai Havertz (muscle), and Max Dowman (ankle) are all in contention to return to the squad, with Odegaard and Havertz especially close. Bukayo Saka and Leandro Trossard both picked up minor issues against Wolves, but neither is expected to miss out, leaving Mikel Arteta with near full-strength options heading into the clash.
Tottenham vs Arsenal Picks
Wednesday’s stalemate will serve as a wake-up call for Arsenal, who will respond here with a victory. However, they’ve conceded to Spurs in four of the last five meetings. Take the Gunners to win, and both teams to score.
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Quinn Allen is a sports writer from Vancouver, Canada. His expertise spans across many sports, but he tends to write mostly European soccer betting previews for BettingTop10 Canada. He’s been in the industry for seven years. Quinn loves to be active in his free time, whether it’s working out, walking, or playing soccer.

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