Las Vegas Raiders vs Los Angeles Rams: NFL Predictions, Odds & Picks | Week 7

Jason Green
By: Jason Green
NFL Picks
NFL Raiders vs Rams

Sunday, October 25, 2026 · 4:25 PM ET · Allegiant Stadium, Las Vegas, NV · FOX

Las Vegas Raiders vs Los Angeles Rams Best Odds

Odds courtesy of Bet365, correct at time of writing and subject to change.

Kirk Cousins and the Raiders have dropped three straight since a 3-0 start, and now they draw a Rams’ team that has a lot of question marks after a bad start. Los Angeles arrives at 2-4, but Matthew Stafford's passing offence still ranks second in passing yards per game. This non-conference affair is key for both teams, who need a W to stay in their division races.

Las Vegas Raiders vs Los Angeles Rams Best Bet

Los Angeles Rams -4.5: -108

I'm backing the Rams to cover the 4.5-point spread. Los Angeles's defence ranks second against the pass, against a Raiders offence that has relied on the pass with little success on the ground.Las Vegas ranks 28th in yards allowed and 30th in rushing offence, so Cousins' 8th-ranked passing attack will have to carry more than usual on the road. That will not happen with Stafford guiding L.A, to the win, where they will cover. 

Kyren Williams Anytime Touchdown: -190

Williams has scored a touchdown in four of Los Angeles's six games this season and remains the clear red-zone option even as Blake Corum cuts into his early-down touches. Las Vegas ranks 28th in the league in rushing yards allowed (134.3 per game), which is why I still like Williams to find paydirt despite the shared backfield.

Bet on Las Vegas Raiders vs Los Angeles Rams
Rams -4.5 (-108)
Bet Now
Bet on Las Vegas Raiders vs Los Angeles Rams
Under 48.5 (-112)
Bet Now

Odds from Bet365 and Sports Interaction, correct at time of writing and subject to change.

Las Vegas Raiders vs Los Angeles Rams Analysis

The Las Vegas side

Cousins has started every game for the Raiders this season and threw for 313 yards with two touchdowns in last week's 33-30 loss to Buffalo. However, the supporting cast is thin: Las Vegas ranks 30th in rushing offence. The Raiders have allowed 30 or more points in three of their last four games, and that mix of a stalled run game and a leaky defence is why I don't trust the home side to keep this within 4.5 points. 

The Los Angeles side

Stafford went 25 of 33 for 222 yards and two touchdowns without an interception in last week's 18-16 loss to Arizona, even though his streak of four straight 300-yard games ended. Los Angeles's passing attack ranks second in the league, and Williams and Corum share a backfield that ranks in the middle of the pack in terms of rushing yards per game. Stafford and company need to get back on track and will in this game face a Raiders’ D that has issues.

bet365
Bet365
sports-interaction
Sports Interaction
Rams Moneyline Under 48.5 
-213-112
Bet Safety Net Up To C$1,000 or Bet C$10 and Get C$50 in Bonus Bets125% Welcome Bonus Up To C$750
Bet NowBet Now

Bet365 and Sports Interaction odds, correct at time of writing and subject to change.

Las Vegas Raiders vs Los Angeles Rams Prediction

The de-vigged market has the Rams at 65% to win outright against 35% for the Raiders. My own number sits a few points higher for Los Angeles, at 68%-32%, because of the Rams ability to run the ball, which the Raiders have not had.That's the real NFL prediction odds angle the public may be missing this week, which is why I'm leaning on the spread for the Lions  rather than just the moneyline.

Outcome

Market-Implied Probability

Our Estimate

Las Vegas Raiders Win

35%

32%

Los Angeles Rams Win

65%

68%

Las Vegas Raiders – Last 5 Games

Opponent

Score

Result

@ Los Angeles Chargers

26-14

W

@ New Orleans Saints

35-27

W

vs Kansas City Chiefs

27-30

L

@ New England Patriots

17-45

L

vs Buffalo Bills

30-33

L

Los Angeles Rams – Last 5 Games

Opponent

Score

Result

vs New York Giants

28-6

W

@ Denver Broncos

26-30

L

@ Philadelphia Eagles

24-20

W

vs Buffalo Bills

34-37 (OT)

L

vs Arizona Cardinals

16-18

L

My Exact Score Prediction: Los Angeles Rams 27 Las Vegas Raiders 20

I'm calling a 27-20 Rams win that covers the 4.5-point spread comfortably. Stafford should move the ball against a Raiders defence allowing 371.7 yards a game, while Los Angeles's own defence keeps Cousins from turning this into a high-scoring one. The 47-point combined total lands just under the posted 48.5 line, which is why my call is the Rams -4.5 with the Under 48.5 being the picks.