NFC And AFC Conference Championship Game Odds, Spread, And Lines

Alex Murray
Alex Murray
24 Jan 23
Betting Magazine
NFC And AFC Conference Championship Game Odds, Spread, And Lines

The NFL has enjoyed quite a start to their 2022 playoff tournament, with lots of big underdogs covering big time spreads and some top teams bowing out early. It’s been an unpredictable and wild ride over the past two weeks for people that are into NFL betting, and that’s likely to continue as the NFL’s top four teams—the San Francisco 49ers, the Philadelphia Eagles, the Cincinnati Bengals, and the Kansas City Chiefs—duke it out on Sunday for a ticket to Super Bowl LVII.


  • Breaking down the best odds for both NFL Conference Championship Games
  • The Eagles offense going up against the 49ers defense.
  • The Bengals take on the AFC crown once again?

NFL Conference Championship Sunday Odds, Lines, And Spreads

Considering the fact that Conference Championship Sunday features the last four teams standing, it should be no surprise that the spreads are about as tight as can possibly be on all of the top sports betting sites. The table below breaks down the best odds for the major markets for both NFL Conference Championship Games.

Sunday, Jan 29 - 3PMSpreadTotalMoneyline
San Francisco 49ers+2.5 (+100)OVER 45.5 (-110+125
Philadelphia Eagles-2.5 (-120)UNDER 45.5 (-110)-145
Sunday, Jan 29 - 630PMSpreadTotalMoneyline
Cincinnati Bengals-1.0 (-110)OVER 47.0 (-110)-115
Kansas City Chiefs+1.0 (-110)UNDER 47.0 (-110)-105

(2) San Francisco 49ers at (1) Philadelphia Eagles Odds

The 49ers, who have won 12 games in a row, will head to the City of Brotherly Love to take on the Eagles, the top seed in the NFC. While both teams are well-rounded, the focus will be on the Eagles offense, which was first in yards and points, going up against the 49ers defense, which was also first in yards and points. This one’s got the makings of a classic.

The 49ers are led by rookie quarterback Brock Purdy, who was the last pick in the draft and is now leading a team in the Conference Championship. San Francisco’s defense is athletic and elite at all three levels, and their cache of offensive weapons is going to be tough for anyone to handle. Something to watch, however, is 49ers running back Christian McCaffrey’s health, as he missed some time last week due to a calf issue.

Philadelphia has looked unstoppable for most of this season, and that was true again in their 31-7 defeat of the New York Giants in last week’s Divisional Round. The Eagles have one of the most explosive offenses in football, led by dual threat quarterback Jalen Hurts. They’re no slouch on the defensive side either, however, as they put up a league-leading 70 sacks this season, the third best mark all-time.

(3) Cincinnati Bengals at (1) Kansas City Chiefs Odds

The Bengals will once again make the trip to Arrowhead Stadium to take on the Chiefs for the AFC crown, just like they did last season. The Bengals won last year in Kansas City, and have actually beaten the top-seeded Chiefs three straight times. You don’t often see the lower-seeded coming in as a betting favorite, but that’s what Cincinnati has done here, though they are only very slight one-point chalk.

Cincinnati, much like the 49ers in the NFC, are the lower seed, but they’re arguably the much hotter club, having won 10 straight games going all the way back to Halloween. Joe Burrow continues to make his case as the best quarterback in the game, and his top weapon and college buddy, wideout Ja’Marr Chase, has looked excellent since his return from injury. The Cincy defense is none too shabby either.

The Chiefs are the top seed and will get to play this one at home in front of one of the best crowds in the NFL, but the health of quarterback Patrick Mahomes weighs heavily here. He was hobbling around during last week’s 27-20 win over the Jaguars after rolling his ankle, so his ability to be mobile out there will be huge. Kansas City’s defense will have its work cut out for it as well.

Betting Trends

  • The Eagles are 7-3 ATS as the home favorite this season
  • The 49ers are 12-2 ATS against NFC opponents this season
  • The Bengals are 10-1 ATS against non-division opponents this season

Alex is a recent graduate of Ryerson's Sport Media program in 2019 and has been contributing to BettingTop10 since 2020. He has worked in the field of sports and sports betting for several years, including writing for theScore and daily fantasy sports website FantasyPros as one of their lead NBA news writers. A dedicated sports fan and experienced sports bettor, Alex has the knowledge to provide you with the best betting advice and the sneakiest props no matter what the sport may be.