NFL Picks

It was another close but no cigar week for us in Week 5, going 2-for-3 on our player props. But we’re starting to pick up some steam here as the season goes on. Check out our player props best bets for Week 6 as well as the latest betting odds!

Dallas arrives at Lambeau Field with the NFL's 31st-ranked defence in total yards allowed, while Green Bay is coming off a 31-7 win over Chicago. The two teams last met in a wild 40-40 tie in September 2025, the night Micah Parsons first returned to Dallas after his trade to Green Bay.

Buffalo arrives at Allegiant Stadium off a wild overtime escape against the Rams, while Las Vegas is coming off a 45-17 blowout loss to New England. Both defences have been generous, Buffalo ranks 28th and Las Vegas 22nd in points allowed, setting up a Week 6 matchup that may be a barnburner.

The Kansas City Chiefs carry a perfect 4-0 record into Arrowhead Stadium against a Los Angeles Chargers team still searching for its first win, with the AFC West rivals meeting for the for the first time this season. The Chiefs’ offence is averaging 29.5 ppg, a sharp contrast with a Chargers’ unit managing just 16.8 ppg.

The 1-4 Arizona Cardinals travel to SoFi Stadium on Sunday riding a four-game losing streak, while the Los Angeles Rams look to bounce back from an overtime loss to Buffalo. A 12.5-point spread, among the widest on this week's board, puts both the margin and the total in play.

Pittsburgh heads to Tampa Bay on the back of a 34-22 win over Indianapolis, while the Buccaneers got their first win of the season in their last game behind Jalon Daniels with Baker Mayfield still sidelined by a thumb injury.

Carolina arrives at Lincoln Financial Field as a narrow road favourite after Philadelphia has dropped three straight games. To make matters worse, Philly QB Jalen Hurts is out for this NFC clash with a blood clot in his calf.

The New York Giants host the New Orleans Saints at MetLife Stadium on Sunday, with them atop the NFC East and New Orleans has lost three in a row and is searching for defensive answers after allowing 30-plus points in three of its five games

The Indianapolis Colts host a winless Tennessee Titans team on Sunday in this AFC South matchup, with Jonathan Taylor's ground game facing a Titans run defence that ranks 17th in the NFL in run defence.

New England carries a two-game winning streak over the Jets into Sunday's AFC East date at Gillette Stadium.New York has a bangled-up offensive line and is a low scoring team that faces a Patriots’ team that lit it up for 45 points in their last game.